| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | What Lies Beneath (2000) | £2,258,893 | £2,258,893 | £2,258,893 | new | 1 |
| 2 (1) |  | Dinosaur (2000) | £2,016,209 | £2,736,511 | £4,864,729 | -5% | 2 |
| 3 (2) |  | Road Trip (2000) | £1,225,934 | £2,078,084 | £3,989,814 | -36% | 2 |
| 4 (3) |  | Billy Elliot (2000) | £1,142,988 | £2,110,343 | £9,312,846 | -23% | 4 |
| 5 (15) |  | The Little Vampire (2000) | £512,708 | £607,214 | £667,014 | 88% | 2 |
| 6 (4) |  | Nutty Professor II: The Klumps (2000) | £485,504 | £779,171 | £4,087,739 | -52% | 3 |
| 7 (new) |  | Coyote Ugly (2000) | £360,683 | £360,683 | £360,683 | new | 1 |
| 8 (5) |  | Hollow Man (2000) | £310,479 | £595,524 | £5,449,751 | -54% | 4 |
| 9 (6) |  | Romeo Must Die (2000) | £281,609 | £511,296 | £1,063,125 | -49% | 2 |
| 10 (new) |  | Bring It On (2000) | £272,848 | £272,848 | £272,848 | new | 1 |
| 11 (new) |  | Memento (2000) | £90,642 | £90,642 | £90,642 | new | 1 |
| 12 (10) |  | O Brother, Where Art Thou? (2000) | £79,430 | £158,764 | £2,693,598 | -49% | 6 |
| 13 (7) |  | Scary Movie (2000) | £76,828 | £175,684 | £9,955,478 | -67% | 7 |
| 14 (11) | | The House of Mirth (2000) | £73,965 | £122,914 | £211,834 | -17% | 2 |
| 15 (9) |  | Snatch (2000) | £71,073 | £160,496 | £12,137,698 | -64% | 8 |