| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Charlie's Angels (2000) | £3,182,114 | £3,182,114 | £3,182,114 | new | 1 |
| 2 (1) |  | What Lies Beneath (2000) | £540,882 | £892,791 | £11,545,516 | -33% | 6 |
| 3 (5) |  | Billy Elliot (2000) | £356,434 | £701,276 | £15,650,760 | -32% | 9 |
| 4 (2) |  | Bedazzled (2000) | £355,866 | £592,011 | £2,761,714 | -49% | 3 |
| 5 (3) |  | Little Nicky (2000) | £273,249 | £457,238 | £1,031,575 | -52% | 2 |
| 6 (4) |  | Pitch Black (2000) | £269,474 | £499,308 | £2,316,912 | -50% | 3 |
| 7 (6) |  | Dinosaur (2000) | £261,935 | £305,888 | £13,030,188 | -30% | 7 |
| 8 (8) |  | The Little Vampire (2000) | £209,667 | £228,505 | £3,980,137 | -14% | 7 |
| 9 (7) |  | The Kid (2000) | £190,259 | £236,364 | £996,451 | -29% | 3 |
| 10 (10) |  | Coyote Ugly (2000) | £186,499 | £327,918 | £3,046,864 | -18% | 6 |
| 11 (new) | | The Skulls (2000) | £149,297 | £149,297 | £149,297 | new | 1 |
| 12 (9) |  | Road Trip (2000) | £101,749 | £209,455 | £7,790,447 | -58% | 7 |
| 13 (15) |  | Memento (2000) | £80,866 | £127,528 | £881,509 | 6% | 6 |
| 14 (11) |  | The Way of the Gun (2000) | £63,772 | £167,277 | £358,446 | -67% | 2 |
| 15 (12) |  | Wonder Boys (2000) | £57,022 | £107,617 | £869,951 | -44% | 4 |