| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | The Others (2001) | £2,259,538 | £2,259,538 | £2,259,538 | new | 1 |
| 2 (1) |  | American Pie 2 (2001) | £1,003,591 | £1,861,835 | £15,788,569 | -38% | 4 |
| 3 (2) |  | Legally Blonde (2001) | £871,872 | £1,631,865 | £3,085,013 | -40% | 2 |
| 4 (3) |  | Jeepers Creepers (2001) | £708,434 | £1,432,301 | £5,047,942 | -38% | 3 |
| 5 (4) |  | Atlantis: The Lost Empire (2001) | £588,630 | £1,420,287 | £5,495,899 | -47% | 4 |
| 6 (5) |  | America's Sweethearts (2001) | £499,486 | £1,047,783 | £4,837,215 | -48% | 3 |
| 7 (new) |  | The Animal (2001) | £345,651 | £345,651 | £345,651 | new | 1 |
| 8 (6) |  | Moulin Rouge (2001) | £318,880 | £665,694 | £17,047,358 | -33% | 9 |
| 9 (7) |  | The Man Who Wasn't There (2001) | £271,800 | £494,174 | £913,783 | -35% | 2 |
| 10 (8) |  | Amélie (2001) | £215,305 | £417,586 | £3,077,241 | -21% | 5 |
| 11 (10) |  | Enigma (2001) | £117,458 | £255,537 | £4,396,187 | -49% | 6 |
| 12 (9) |  | Ashoka the Great (2001) | £104,381 | £182,311 | £417,772 | -56% | 2 |
| 13 (11) |  | Cats & Dogs (2001) | £94,672 | £300,932 | £23,013,391 | -55% | 14 |
| 14 (14) | | The Pledge (2001) | £63,898 | £120,530 | £652,533 | -39% | 4 |
| 15 (12) |  | Mike Bassett: England Manager (2001) | £62,524 | £126,894 | £3,443,174 | -53% | 6 |