| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Mission:Impossible III (2006) | £5,378,013 | £5,378,013 | £5,378,013 | new | 1 |
| 2 (new) |  | Confetti (2006) | £635,072 | £635,072 | £635,072 | new | 1 |
| 3 (1) |  | Ice Age: The Meltdown (2006) | £584,473 | £1,556,261 | £27,804,478 | -47% | 5 |
| 4 (3) |  | Silent Hill (2006) | £345,337 | £767,700 | £2,955,101 | -49% | 3 |
| 5 (2) |  | 16 Blocks (2006) | £310,184 | £855,613 | £1,634,452 | -60% | 2 |
| 6 (4) |  | Scary Movie 4 (2006) | £195,989 | £515,332 | £5,635,403 | -64% | 4 |
| 7 (5) |  | American Dreamz (2006) | £183,033 | £507,912 | £2,021,886 | -64% | 3 |
| 8 (6) |  | Slither (2006) | £162,462 | £493,379 | £981,825 | -67% | 2 |
| 9 (8) |  | She's the Man (2006) | £132,133 | £349,420 | £4,356,389 | -55% | 5 |
| 10 (7) |  | Inside Man (2006) | £105,434 | £291,637 | £7,927,220 | -66% | 7 |
| 11 (new) |  | 36 China Town (2006) | £83,040 | £83,040 | £83,040 | new | 1 |
| 12 (10) |  | Eight Below (2006) | £67,305 | £273,676 | £1,022,989 | -66% | 3 |
| 13 (9) |  | Take the Lead (2006) | £58,568 | £222,387 | £2,194,696 | -77% | 4 |
| 14 (11) |  | An American Haunting (2006) | £40,107 | £143,757 | £1,758,488 | -78% | 4 |
| 15 (13) | | The Squid and the Whale (2005) | £38,069 | £89,722 | £506,477 | -42% | 5 |