| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Valentine's Day (2010) | £3,732,393 | £3,732,393 | £3,732,393 | new | 1 |
| 2 (1) |  | Avatar (2009) | £3,316,855 | £5,136,271 | £77,072,663 | -24% | 9 |
| 3 (new) |  | The Wolfman (2010) | £2,367,849 | £2,367,849 | £2,367,849 | new | 1 |
| 4 (2) |  | The Princess and the Frog (2010) | £1,504,908 | £1,957,636 | £4,197,395 | -33% | 3 |
| 5 (new) |  | Percy Jackson and the Olympians: The Lightning Thief (2010) | £1,502,663 | £1,502,663 | £1,502,663 | new | 1 |
| 6 (new) |  | My Name Is Khan (2010) | £936,454 | £936,454 | £936,454 | new | 1 |
| 7 (4) |  | Invictus (2009) | £778,146 | £1,394,180 | £2,462,568 | -27% | 2 |
| 8 (new) |  | A Single Man (2010) | £502,009 | £502,009 | £502,009 | new | 1 |
| 9 (8) |  | Alvin and the Chipmunks: The Squeakquel (2009) | £424,622 | £500,018 | £21,337,049 | -42% | 8 |
| 10 (3) |  | Astro Boy (2009) | £422,382 | £534,115 | £1,625,987 | -61% | 2 |
| 11 (5) |  | Sherlock Holmes (2009) | £391,913 | £688,509 | £25,162,902 | -50% | 8 |
| 12 (7) |  | Youth In Revolt (2010) | £368,019 | £746,250 | £1,490,182 | -51% | 2 |
| 13 (6) |  | Edge of Darkness (2010) | £301,086 | £651,316 | £3,302,594 | -61% | 3 |
| 14 (9) |  | Its Complicated (2009) | £200,720 | £549,103 | £8,838,051 | -64% | 6 |
| 15 (11) |  | Precious: Based On the Novel Push By Sapphire (2009) | £181,714 | £398,654 | £1,211,445 | -51% | 3 |
| 16 (new) |  | Ponyo (2008) | £171,857 | £171,857 | £171,857 | new | 1 |
| 17 (21) |  | Planet 51 (2009) | £51,427 | £51,835 | £4,748,118 | 53% | 11 |
| 18 (new) |  | Battle For Terra (2009) | £24,748 | £24,748 | £24,748 | new | 1 |
| 19 (18) |  | Sex & Drugs & Rock & Roll (2010) | £15,378 | £39,591 | £787,235 | -54% | 6 |
| 20 (19) |  | An Education (2009) | £13,818 | £40,977 | £2,205,230 | -53% | 15 |
| 21 (20) |  | Nine (2009) | £10,327 | £41,738 | £3,209,300 | -58% | 9 |
| 22 (16) |  | St. Trinian's 2: The Legend of Frittons Gold (2009) | £9,735 | £14,320 | £7,034,034 | -85% | 9 |
| 23 (new) | | Food Inc. (2010) | £5,134 | £5,134 | £5,134 | new | 1 |
| 24 (23) |  | Nowhere Boy (2009) | £2,247 | £16,368 | £1,261,090 | -78% | 8 |
| 25 (24) | | Mugabe and the White African (2010) | £1,608 | £8,060 | £49,249 | -64% | 6 |
| 26 (new) |  | Anonyma: A Woman In Berlin (2010) | £1,406 | £1,406 | £1,406 | new | 1 |
| 27 (30) |  | The Boys Are Back (2010) | £1,273 | £1,900 | £126,264 | 52% | 4 |
| 28 (new) | | Eamon (2010) | £1,024 | £1,024 | £1,024 | new | 1 |
| 29 (new) |  | Winter In Wartime (2010) | £898 | £898 | £898 | new | 1 |
| 30 (25) |  | Holy Water (2010) | £849 | £3,784 | £8,283 | -81% | 2 |
| 31 (26) |  | 44 Inch Chest (2010) | £824 | £2,991 | £398,194 | -77% | 5 |
| 32 (34) |  | Harry Brown (2009) | £584 | £2,076 | £4,557,483 | 62% | 13 |
| 33 (33) | | Bright Star (2009) | £582 | £3,139 | £1,060,141 | 59% | 14 |
| 34 (28) | | Me and Orson Welles (2008) | £91 | £6,652 | £458,609 | -94% | 10 |
| 35 (31) |  | Nativity! (2009) | £20 | £210 | £5,187,402 | -94% | 12 |
| 36 (32) |  | Glorious 39 (2009) | £20 | £8,644 | £297,200 | -94% | 12 |