| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (2) |  | Avatar (2009) | £2,817,009 | £6,192,821 | £83,265,484 | -15% | 10 |
| 2 (4) |  | The Princess and the Frog (2010) | £1,725,519 | £4,675,938 | £8,873,333 | 13% | 4 |
| 3 (new) |  | The Lovely Bones (2009) | £1,637,579 | £1,637,579 | £1,637,579 | new | 1 |
| 4 (1) |  | Valentine's Day (2010) | £1,583,142 | £4,044,761 | £7,777,154 | -58% | 2 |
| 5 (5) |  | Percy Jackson and the Olympians: The Lightning Thief (2010) | £1,487,446 | £3,722,433 | £5,225,096 | -1% | 2 |
| 6 (3) |  | The Wolfman (2010) | £774,890 | £1,804,029 | £4,171,878 | -67% | 2 |
| 7 (new) |  | Solomon Kane (2009) | £611,886 | £611,886 | £611,886 | new | 1 |
| 8 (9) |  | Alvin and the Chipmunks: The Squeakquel (2009) | £608,154 | £1,827,810 | £23,164,859 | 30% | 9 |
| 9 (7) |  | Invictus (2009) | £570,801 | £1,192,794 | £3,655,362 | -27% | 3 |
| 10 (10) |  | Astro Boy (2009) | £523,215 | £1,476,340 | £3,102,327 | 19% | 3 |
| 11 (6) |  | My Name Is Khan (2010) | £448,747 | £1,023,895 | £1,960,349 | -52% | 2 |
| 12 (8) |  | A Single Man (2010) | £377,751 | £765,172 | £1,267,181 | -25% | 2 |
| 13 (11) |  | Sherlock Holmes (2009) | £214,110 | £548,832 | £25,711,734 | -45% | 9 |
| 14 (12) |  | Youth In Revolt (2010) | £154,021 | £432,331 | £1,922,513 | -58% | 3 |
| 15 (new) |  | The Last Station (2010) | £135,368 | £135,368 | £135,368 | new | 1 |