| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Alice In Wonderland (2010) | £10,555,220 | £10,555,220 | £10,555,220 | new | 1 |
| 2 (1) |  | Avatar (2009) | £908,049 | £1,948,365 | £88,748,017 | -60% | 12 |
| 3 (3) |  | The Crazies (2010) | £673,551 | £1,319,960 | £2,514,167 | -44% | 2 |
| 4 (2) |  | The Lovely Bones (2009) | £661,595 | £1,335,189 | £5,183,763 | -45% | 3 |
| 5 (4) |  | The Princess and the Frog (2010) | £381,760 | £502,128 | £10,487,623 | -56% | 6 |
| 6 (8) |  | From Paris With Love (2010) | £374,620 | £765,380 | £1,444,330 | -45% | 2 |
| 7 (5) |  | Percy Jackson and the Olympians: The Lightning Thief (2010) | £369,938 | £547,909 | £6,960,947 | -57% | 4 |
| 8 (7) |  | Leap Year (2010) | £364,875 | £750,905 | £1,479,156 | -50% | 2 |
| 9 (6) |  | Valentine's Day (2010) | £296,561 | £647,441 | £9,977,602 | -64% | 4 |
| 10 (9) |  | A Single Man (2010) | £219,243 | £461,511 | £2,411,861 | -43% | 4 |
| 11 (new) |  | Legion (2010) | £212,328 | £212,328 | £212,328 | new | 1 |
| 12 (re) |  | Crazy Heart (2009) | £210,042 | £210,042 | £492,990 | re | 1 |
| 13 (new) |  | Case 39 (2010) | £183,088 | £183,088 | £183,088 | new | 1 |
| 14 (10) |  | Invictus (2009) | £140,310 | £312,196 | £4,537,276 | -52% | 5 |
| 15 (new) |  | Chloe (2010) | £135,540 | £135,540 | £135,540 | new | 1 |
| 16 (new) |  | Exit Through the Gift Shop (2010) | £103,654 | £103,654 | £103,654 | new | 1 |
| 17 (new) |  | Ondine (2010) | £102,138 | £102,138 | £102,138 | new | 1 |
| 18 (new) | | Atithi Tum Kab Jaoge (2010) | £47,812 | £47,812 | £47,812 | new | 1 |
| 19 (20) |  | An Education (2009) | £40,825 | £78,028 | £2,396,929 | 6% | 17 |
| 20 (new) | | Father of My Children (2010) | £24,194 | £24,194 | £24,194 | new | 1 |
| 21 (22) |  | Planet 51 (2009) | £13,462 | £13,698 | £4,939,460 | -30% | 13 |
| 22 (new) |  | The Shouting Men (2010) | £4,265 | £4,265 | £4,265 | new | 1 |
| 23 (26) |  | Nine (2009) | £2,281 | £12,259 | £3,256,830 | -59% | 11 |
| 24 (25) |  | Sex & Drugs & Rock & Roll (2010) | £1,985 | £11,172 | £852,500 | -76% | 8 |
| 25 (29) |  | Glorious 39 (2009) | £1,072 | £5,334 | £314,405 | -30% | 14 |
| 26 (31) |  | Nowhere Boy (2009) | £1,037 | £9,719 | £1,292,610 | -6% | 10 |
| 27 (33) | | Mugabe and the White African (2010) | £893 | £10,727 | £70,880 | 17% | 8 |
| 28 (27) |  | The Boys Are Back (2010) | £498 | £3,921 | £135,813 | -80% | 6 |
| 29 (30) | | She, a Chinese (2009) | £472 | £8,217 | £9,567 | -65% | 2 |
| 30 (35) |  | 44 Inch Chest (2010) | £440 | £1,616 | £401,724 | 88% | 7 |
| 31 (28) |  | St. Trinian's 2: The Legend of Frittons Gold (2009) | £153 | £824 | £7,075,203 | -93% | 11 |