| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Date Night (2010) | £1,272,405 | £1,272,405 | £1,272,405 | new | 1 |
| 2 (2) |  | Clash of the Titans (2010) | £985,344 | £1,797,236 | £18,070,779 | -37% | 4 |
| 3 (3) |  | How to Train Your Dragon (2010) | £821,638 | £1,167,572 | £14,256,991 | -36% | 4 |
| 4 (1) |  | Dear John (2010) | £812,287 | £1,581,342 | £3,576,643 | -59% | 2 |
| 5 (4) |  | Kick-Ass (2010) | £635,270 | £1,200,546 | £10,241,210 | -30% | 4 |
| 6 (6) |  | The Ghost (2010) | £631,032 | £1,193,859 | £2,047,538 | -26% | 2 |
| 7 (new) |  | It's a Wonderful Afterlife (2010) | £464,468 | £464,468 | £464,468 | new | 1 |
| 8 (5) |  | Nanny Mcphee and the Big Bang (2010) | £397,371 | £602,728 | £15,169,311 | -54% | 5 |
| 9 (7) |  | Alice In Wonderland (2010) | £278,855 | £492,517 | £41,915,826 | -44% | 8 |
| 10 (new) |  | The Joneses (2009) | £247,178 | £247,178 | £247,178 | new | 1 |
| 11 (re) |  | Cemetery Junction (2010) | £202,587 | £202,587 | £1,132,948 | re | 1 |
| 12 (8) |  | The Blind Side (2010) | £131,153 | £303,499 | £5,933,635 | -56% | 5 |
| 13 (new) |  | Centurion (2010) | £114,147 | £114,147 | £114,147 | new | 1 |
| 14 (11) |  | Shutter Island (2010) | £82,495 | £168,627 | £10,599,763 | -54% | 7 |
| 15 (9) |  | Remember Me (2010) | £70,866 | £208,729 | £3,572,119 | -69% | 4 |
| 16 (12) | | The Infidel (2010) | £66,100 | £122,745 | £442,950 | -45% | 3 |
| 17 (new) | | Agora (2010) | £31,530 | £31,530 | £31,530 | new | 1 |
| 18 (new) | | Extract (2010) | £26,714 | £26,714 | £26,714 | new | 1 |
| 19 (new) |  | Ekam Son of Soil (2010) | £26,048 | £26,048 | £26,048 | new | 1 |
| 20 (new) | | Dogtooth (2009) | £26,013 | £26,013 | £26,013 | new | 1 |
| 21 (new) |  | Life During Wartime (2010) | £15,768 | £15,768 | £15,768 | new | 1 |
| 22 (new) | | La Danse the Paris Opera (2010) | £9,321 | £9,321 | £9,321 | new | 1 |
| 23 (new) |  | Cherrybomb (2010) | £6,860 | £6,860 | £6,860 | new | 1 |
| 24 (16) | | Perriers Bounty (2010) | £5,992 | £15,336 | £331,813 | -52% | 5 |
| 25 (17) |  | Planet 51 (2009) | £5,787 | £13,089 | £5,035,879 | -29% | 20 |
| 26 (23) |  | No Greater Love (2010) | £3,543 | £4,236 | £11,219 | 53% | 3 |
| 27 (25) | | Mugabe and the White African (2010) | £731 | £824 | £82,815 | -42% | 15 |
| 28 (19) | | The Heavy (2010) | £654 | £4,577 | £9,714 | -87% | 2 |
| 29 (18) |  | Exit Through the Gift Shop (2010) | £618 | £5,453 | £306,169 | -89% | 8 |
| 30 (new) | | The Calling (2010) | £567 | £567 | £567 | new | 1 |
| 31 (24) |  | An Education (2009) | £519 | £4,179 | £2,529,801 | -66% | 24 |
| 32 (21) | | Crying With Laughter (2010) | £48 | £3,157 | £6,804 | -99% | 2 |