| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Robin Hood (2010) | £5,750,332 | £5,750,332 | £5,750,332 | new | 1 |
| 2 (1) |  | Iron Man 2 (2010) | £1,595,612 | £2,815,439 | £17,905,902 | -50% | 3 |
| 3 (3) |  | A Nightmare On Elm Street (2010) | £649,323 | £1,334,352 | £2,677,189 | -52% | 2 |
| 4 (4) |  | Hot Tub Time Machine (2010) | £573,122 | £1,079,849 | £1,984,808 | -37% | 2 |
| 5 (2) |  | Furry Vengeance (2010) | £548,440 | £694,999 | £2,473,049 | -69% | 2 |
| 6 (6) |  | Four Lions (2010) | £496,649 | £835,756 | £1,444,364 | -18% | 2 |
| 7 (5) |  | The Back Up Plan (2010) | £478,917 | £888,788 | £1,598,989 | -33% | 2 |
| 8 (7) |  | How to Train Your Dragon (2010) | £254,638 | £323,690 | £16,729,312 | -51% | 7 |
| 9 (8) |  | The Last Song (2010) | £181,489 | £280,084 | £1,832,362 | -46% | 3 |
| 10 (9) |  | Date Night (2010) | £127,785 | £274,132 | £3,795,016 | -62% | 4 |
| 11 (11) |  | The Ghost (2010) | £119,980 | £250,447 | £3,840,476 | -57% | 5 |
| 12 (13) |  | Nanny Mcphee and the Big Bang (2010) | £95,412 | £114,036 | £16,211,057 | -44% | 8 |
| 13 (10) |  | Clash of the Titans (2010) | £68,227 | £172,209 | £20,111,003 | -77% | 7 |
| 14 (12) |  | Dear John (2010) | £61,543 | £154,833 | £5,445,790 | -73% | 5 |
| 15 (14) |  | Kick-Ass (2010) | £51,777 | £107,293 | £11,528,933 | -62% | 7 |