| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (1) |  | Sex and the City 2 (2010) | £2,473,043 | £7,509,334 | £13,652,052 | -60% | 2 |
| 2 (2) |  | StreetDance 3D (2010) | £1,144,239 | £3,671,902 | £8,964,747 | -37% | 3 |
| 3 (3) |  | Prince of Persia: The Sands of Time (2010) | £821,661 | £2,344,999 | £6,362,459 | -50% | 3 |
| 4 (new) |  | Death At a Funeral (2010) | £696,280 | £696,280 | £696,280 | new | 1 |
| 5 (4) |  | Robin Hood (2010) | £647,195 | £1,912,044 | £13,532,135 | -57% | 4 |
| 6 (5) |  | Tooth Fairy (2010) | £538,366 | £1,595,585 | £2,440,474 | -36% | 2 |
| 7 (new) |  | 4.3.2.1 (2010) | £433,218 | £433,218 | £433,218 | new | 1 |
| 8 (new) |  | She's Out of My League (2010) | £400,554 | £400,554 | £400,554 | new | 1 |
| 9 (6) |  | Iron Man 2 (2010) | £226,314 | £710,990 | £20,686,508 | -56% | 6 |
| 10 (7) |  | Space Chimps 2: Zartog Strikes Back (2010) | £220,989 | £822,247 | £1,257,130 | -49% | 2 |
| 11 (new) | | Raajneeti (2010) | £218,783 | £218,783 | £218,783 | new | 1 |
| 12 (new) |  | The Killer Inside Me (2010) | £124,006 | £124,006 | £124,006 | new | 1 |
| 13 (8) |  | The Losers (2010) | £110,255 | £496,395 | £888,333 | -72% | 2 |
| 14 (11) |  | Furry Vengeance (2010) | £91,042 | £354,260 | £3,301,901 | -42% | 5 |
| 15 (10) |  | Four Lions (2010) | £83,609 | £223,835 | £2,562,809 | -49% | 5 |