| Title | Weekend | Week | Total | % Change | Total Weeks | ||
| 1 (1) | ![]() | The Other Guys (2010) | £976,459 | £1,622,907 | £6,030,653 | -24% | 3 |
| 2 (3) | ![]() | The Town (2010) | £890,309 | £1,606,703 | £2,611,742 | -11% | 2 |
| 3 (new) | ![]() | Buried (2010) | £820,631 | £820,631 | £820,631 | new | 1 |
| 4 (2) | ![]() | Eat Pray Love (2010) | £800,533 | £1,700,461 | £2,865,695 | -31% | 2 |
| 5 (4) | ![]() | The Hole (2010) | £700,763 | £974,590 | £1,881,312 | -23% | 2 |
| 6 (new) | ![]() | Made In Dagenham (2010) | £674,059 | £674,059 | £674,059 | new | 1 |
| 7 (new) | ![]() | Back to the Future (1985) 25th Anniversary | £461,194 | £461,194 | £461,194 | re | 17 |
| 8 (6) | ![]() | Toy Story 3 (2010) | £413,759 | £533,074 | £72,944,299 | -12% | 11 |
| 9 (5) | ![]() | Devil (2010) | £332,949 | £638,296 | £2,488,305 | -37% | 3 |
| 10 (7) | ![]() | Grown Ups (2010) | £302,196 | £467,294 | £7,372,455 | -21% | 6 |
| 11 (new) | ![]() | Endhiran (2010) | £284,600 | £284,600 | £284,600 | new | 1 |
| 12 (10) | ![]() | Marmaduke (2010) | £278,154 | £300,275 | £5,112,408 | 12% | 7 |
| 13 (11) | ![]() | Diary of a Wimpy Kid (2010) | £209,338 | £235,174 | £2,522,578 | 2% | 6 |
| 14 (new) | ![]() | Takers (2010) | £208,390 | £208,390 | £208,390 | new | 1 |
| 15 (new) | ![]() | Anjaana Anjaani (2010) | £183,989 | £183,989 | £183,989 | new | 1 |
| 16 (15) | Winter's Bone (2010) | £100,432 | £316,432 | £884,677 | -21% | 3 | |
| 17 (9) | ![]() | Tamara Drewe (2010) | £98,613 | £291,901 | £2,395,860 | -60% | 4 |
| 18 (19) | The Illusionist (2010) | £12,579 | £24,168 | £807,012 | -15% | 7 | |
| 19 (new) | Police Adjective (2010) | £10,879 | £10,879 | £10,879 | new | 1 | |
| 20 (re) | ![]() | The Secret of Kells (2009) | £6,151 | £6,151 | £31,808 | re | 2 |
| 21 (21) | ![]() | Soulboy (2010) | £2,044 | £11,040 | £68,522 | -50% | 3 |
| 22 (new) | ![]() | Bella (2007) | £786 | £786 | £786 | new | 1 |
| 23 (new) | Collapse (2010) | £661 | £661 | £661 | new | 1 | |
| 24 (re) | London River (2010) | £601 | £601 | £99,855 | re | 12 | |
| 25 (new) | Little Big Soldier (2010) | £124 | £124 | £124 | new | 1 | |
| 26 (re) | ![]() | Cherry Tree Lane (2010) | £52 | £52 | £3,477 | re | 3 |