| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (1) |  | The Secret Life of Pets (2016) | £4,739,295 | £7,035,686 | £16,615,725 | -51% | 2 |
| 2 (new) |  | Absolutely Fabulous: The Movie (2016) | £4,042,959 | £4,042,959 | £4,042,959 | new | 1 |
| 3 (new) |  | Central Intelligence (2016) | £3,050,261 | £3,050,261 | £3,050,261 | new | 1 |
| 4 (2) |  | Independence Day: Resurgence (2016) | £2,023,664 | £4,087,969 | £9,155,824 | -60% | 2 |
| 5 (3) |  | The Conjuring 2: The Enfield Case (2016) | £823,957 | £1,722,273 | £9,457,326 | -47% | 3 |
| 6 (4) |  | Me Before You (2016) | £355,522 | £908,786 | £8,932,057 | -47% | 5 |
| 7 (5) |  | The Nice Guys (2016) | £100,055 | £227,320 | £3,694,695 | -51% | 5 |
| 8 (9) |  | The Jungle Book (2016) | £80,027 | £109,137 | £45,738,740 | -24% | 12 |
| 9 (6) |  | Alice Through the Looking Glass (2016) | £79,695 | £149,616 | £9,544,781 | -58% | 6 |
| 10 (7) |  | Teenage Mutant Ninja Turtles: Out of the Shadows (2016) | £75,897 | £134,041 | £5,957,182 | -59% | 5 |
| 11 (re) |  | Zootopia (2016) | £60,707 | £60,707 | £23,709,883 | re | 12 |
| 12 (8) |  | X-Men: Apocalypse (2016) | £60,316 | £152,927 | £18,273,403 | -65% | 7 |
| 13 (12) |  | The Angry Birds Movie (2016) | £46,926 | £72,994 | £10,002,458 | -51% | 8 |
| 14 (16) |  | Tale of Tales (2015) | £28,117 | £65,298 | £304,695 | -40% | 3 |
| 15 (10) |  | The Boss (2016) | £26,646 | £89,138 | £1,692,452 | -74% | 4 |