| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (1) |  | Suicide Squad (2016) | £4,241,508 | £10,962,018 | £22,214,243 | -62% | 2 |
| 2 (2) |  | Finding Dory (2016) | £2,567,085 | £7,061,974 | £27,313,178 | -35% | 3 |
| 3 (3) |  | Jason Bourne (2016) | £1,471,495 | £3,400,193 | £17,462,208 | -40% | 3 |
| 4 (4) |  | The BFG (2016) | £1,110,536 | £3,302,260 | £23,510,073 | -35% | 4 |
| 5 (new) |  | Mike and Dave Need Wedding Dates (2016) | £1,068,522 | £1,068,522 | £1,068,522 | new | 1 |
| 6 (new) |  | Pete's Dragon (2016) | £844,090 | £844,090 | £844,090 | new | 1 |
| 7 (new) |  | Nerve (2016) | £803,457 | £803,457 | £803,457 | new | 1 |
| 8 (new) |  | The Shallows (2016) | £800,963 | £800,963 | £800,963 | new | 1 |
| 9 (5) |  | Star Trek: Beyond (2016) | £477,079 | £1,266,141 | £14,211,629 | -47% | 4 |
| 10 (6) |  | The Secret Life of Pets (2016) | £286,076 | £987,213 | £33,058,018 | -36% | 8 |
| 11 (new) | | Mohenjo Daro (2016) | £176,770 | £176,770 | £176,770 | new | 1 |
| 12 (new) |  | Rustom (2016) | £115,267 | £115,267 | £115,267 | new | 1 |
| 13 (7) |  | Ghostbusters (2016) | £113,610 | £390,451 | £10,386,043 | -60% | 5 |
| 14 (new) | | Wiener Dog (2016) | £86,423 | £86,423 | £86,423 | new | 1 |
| 15 (8) |  | Ice Age: Collision Course (2016) | £55,964 | £276,433 | £6,761,873 | -51% | 5 |
| 16 (9) |  | Absolutely Fabulous: The Movie (2016) | £48,246 | £160,298 | £15,768,593 | -43% | 7 |
| 17 (20) |  | Branagh Theatre Live: Romeo and Juliet 2016 (2016) | £40,420 | £42,050 | £811,263 | 88% | 6 |
| 18 (new) | | Valley of Love (2016) | £27,438 | £27,438 | £27,438 | new | 1 |
| 19 (11) |  | Bobby Sands 66 Days (2016) | £27,025 | £72,225 | £118,635 | -42% | 2 |
| 20 (new) | | The Idol (2016) | £19,857 | £19,857 | £19,857 | new | 1 |
| 21 (10) |  | The Legend of Tarzan (2016) | £18,021 | £65,216 | £9,136,933 | -73% | 6 |
| 22 (12) |  | Now You See Me 2 (2016) | £15,249 | £49,216 | £6,258,253 | -67% | 6 |
| 23 (new) |  | The Wave (2016) | £13,064 | £13,064 | £13,064 | new | 1 |
| 24 (new) | | The Confession (2016) | £9,557 | £9,557 | £9,557 | new | 1 |
| 25 (new) | | My Best Friends Wedding (2016) | £6,033 | £6,033 | £6,033 | new | 1 |
| 26 (18) | | Born to Be Blue (2016) | £4,225 | £10,857 | £30,666 | -31% | 3 |
| 27 (new) | | Ingrid Bergman In Her Own Words (2016) | £3,960 | £3,960 | £3,960 | new | 1 |
| 28 (re) | | Almeida Live: Richard III 2016 (2016) | £2,741 | £2,741 | £404,233 | re | 3 |
| 29 (new) | | Karinkunnam 6s (2016) | £2,611 | £2,611 | £2,611 | new | 1 |
| 30 (new) |  | ID2: Shadwell Army (2016) | £2,262 | £2,262 | £2,262 | new | 1 |
| 31 (27) |  | Me Before You (2016) | £1,689 | £5,488 | £9,593,560 | -12% | 11 |
| 32 (new) | | Wagah (2016) | £1,310 | £1,310 | £1,310 | new | 1 |
| 33 (24) | | The Carer (2016) | £1,116 | £4,452 | £7,426 | -62% | 2 |
| 34 (new) | | Babu Bangaram (2016) | £876 | £876 | £876 | new | 1 |
| 35 (31) |  | The Jungle Book (2016) | £806 | £4,996 | £46,113,921 | 25% | 18 |
| 36 (33) |  | Alice Through the Looking Glass (2016) | £633 | £4,661 | £9,669,680 | 62% | 11 |
| 37 (26) | | The Killing$ of Tony Blair (2016) | £327 | £5,363 | £17,730 | -83% | 2 |
| 38 (30) | | Notes On Blindness (2016) | £282 | £3,614 | £77,226 | -63% | 7 |
| 39 (25) |  | Tale of Tales (2015) | £162 | £2,601 | £393,431 | -95% | 9 |