| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | The Girl On the Train (2016) | £6,957,945 | £6,957,945 | £6,957,945 | new | 1 |
| 2 (1) |  | Bridget Jones's Baby (2016) | £2,997,832 | £6,515,792 | £37,866,152 | -38% | 4 |
| 3 (2) |  | Miss Peregrines Home For Peculiar Children (2016) | £2,224,702 | £3,243,264 | £6,717,045 | -36% | 2 |
| 4 (3) |  | Deepwater Horizon (2016) | £987,694 | £1,839,127 | £3,823,467 | -50% | 2 |
| 5 (4) |  | The Magnificent Seven (2016) | £511,539 | £1,016,835 | £5,371,104 | -49% | 3 |
| 6 (6) |  | Finding Dory (2016) | £282,031 | £309,667 | £42,030,294 | -23% | 11 |
| 7 (new) | | War On Everyone (2016) | £187,564 | £187,564 | £187,564 | new | 1 |
| 8 (new) |  | Tristan Und Isolde (2016) | £178,283 | £178,283 | £178,283 | new | 1 |
| 9 (7) |  | Kubo and the Two Strings (2016) | £131,951 | £157,172 | £2,887,889 | -59% | 5 |
| 10 (8) |  | Don't Breathe (2016) | £128,090 | £218,755 | £3,574,939 | -42% | 5 |
| 11 (new) | | My Scientology Movie (2016) | £106,720 | £106,720 | £106,720 | new | 1 |
| 12 (new) | | Remo (2016) | £74,132 | £74,132 | £74,132 | new | 1 |
| 13 (re) |  | The Young Offenders (2016) | £70,717 | £70,717 | £732,461 | re | 3 |
| 14 (9) |  | Bad Moms (2016) | £70,568 | £164,317 | £8,141,704 | -60% | 7 |
| 15 (re) |  | The Secret Life of Pets (2016) | £69,990 | £69,990 | £35,212,308 | re | 11 |
| 16 (12) |  | The BFG (2016) | £68,835 | £76,794 | £30,054,778 | -56% | 12 |
| 17 (new) |  | Blood Father (2016) | £68,808 | £68,808 | £68,808 | new | 1 |
| 18 (11) |  | The Girl With All the Gifts (2016) | £37,130 | £124,336 | £1,011,303 | -78% | 3 |
| 19 (new) |  | I Belonged to You (2016) | £28,058 | £28,058 | £28,058 | new | 1 |
| 20 (18) |  | The Beatles: Eight Days a Week - The Touring Years (2016) | £26,020 | £26,541 | £983,140 | -49% | 4 |
| 21 (19) |  | Brotherhood (2016) | £21,030 | £38,674 | £3,659,032 | -53% | 6 |
| 22 (17) |  | The Infiltrator (2016) | £20,005 | £48,630 | £1,039,466 | -64% | 4 |
| 23 (new) | | Mirzya (2016) | £16,206 | £16,206 | £16,206 | new | 1 |
| 24 (21) |  | Anthropoid (2016) | £14,395 | £37,434 | £750,586 | -49% | 5 |
| 25 (24) |  | Swallows and Amazons (2016) | £11,953 | £18,193 | £3,014,105 | -56% | 8 |
| 26 (new) | | The Greasy Strangler (2016) | £9,063 | £9,063 | £9,063 | new | 1 |
| 27 (26) | | Under the Shadow (2016) | £5,659 | £27,039 | £51,431 | -77% | 2 |
| 28 (new) | | Bir Baba Hindu (2016) | £5,120 | £5,120 | £5,120 | new | 1 |
| 29 (25) |  | Jason Bourne (2016) | £3,817 | £12,400 | £23,105,594 | -85% | 11 |
| 30 (new) | | Mattress Men (2016) | £3,296 | £3,296 | £3,296 | new | 1 |
| 31 (new) | | Mission Milano (2016) | £2,381 | £2,381 | £2,381 | new | 1 |
| 32 (32) | | The Deep Blue Sea: NT Live 2016 (2016) | £1,937 | £15,541 | £713,500 | -41% | 5 |
| 33 (41) | | The Threepenny Opera: NT Live 2016 (2016) | £1,299 | £5,886 | £329,335 | 43% | 3 |
| 34 (30) |  | David Brent: Life On the Road (2016) | £835 | £2,983 | £3,639,605 | -86% | 8 |
| 35 (new) | | The Guvnor (2016) | £762 | £762 | £762 | new | 1 |
| 36 (new) | | Oozham (2016) | £502 | £502 | £502 | new | 1 |
| 37 (new) | | 13th (2016) | £455 | £455 | £455 | new | 1 |
| 38 (35) | | Cymbeline: RSC Live 2016 (2016) | £430 | £149,223 | £229,626 | -67% | 2 |
| 39 (28) |  | The Jungle Book (2016) | £417 | £1,049 | £46,191,905 | -97% | 26 |
| 40 (50) | | Two Women (2016) | £278 | £794 | £6,290 | 86% | 3 |
| 41 (45) |  | Bobby Sands 66 Days (2016) | £166 | £327 | £235,981 | -13% | 10 |
| 42 (38) |  | The Lovers and the Despot (2016) | £44 | £1,720 | £9,662 | -95% | 3 |
| 43 (48) |  | Now You See Me 2 (2016) | £24 | £11,428 | £6,319,592 | -83% | 14 |