| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Doctor Strange (2016) | £9,288,898 | £9,288,898 | £9,288,898 | new | 1 |
| 2 (1) |  | Trolls (2016) | £3,256,912 | £8,560,450 | £14,001,328 | -40% | 2 |
| 3 (2) |  | Jack Reacher Never Go Back (2016) | £1,258,900 | £2,887,573 | £5,576,134 | -53% | 2 |
| 4 (3) |  | The Girl On the Train (2016) | £1,215,472 | £2,695,274 | £20,427,279 | -39% | 4 |
| 5 (8) |  | Storks (2016) | £736,177 | £1,811,433 | £5,236,659 | 9% | 3 |
| 6 (5) |  | Bridget Jones's Baby (2016) | £673,069 | £1,640,220 | £46,171,395 | -40% | 7 |
| 7 (4) |  | Inferno (2016) | £648,287 | £1,486,727 | £7,241,956 | -50% | 3 |
| 8 (new) | | Ae Dil Hai Mushkil (2016) | £617,400 | £617,400 | £617,400 | new | 1 |
| 9 (7) |  | Miss Peregrines Home For Peculiar Children (2016) | £549,103 | £1,513,030 | £11,541,505 | -25% | 5 |
| 10 (6) |  | Ouija: Origin of Evil (2016) | £532,375 | £1,139,845 | £1,919,471 | -32% | 2 |
| 11 (9) |  | I, Daniel Blake (2016) | £476,020 | £883,272 | £1,328,072 | 7% | 2 |
| 12 (13) |  | The Secret Life of Pets (2016) | £139,642 | £386,646 | £35,825,195 | 25% | 14 |
| 13 (10) |  | Keeping Up With the Joneses (2016) | £80,635 | £279,922 | £551,228 | -70% | 2 |
| 14 (15) |  | The BFG (2016) | £72,086 | £210,070 | £30,443,825 | -6% | 15 |
| 15 (14) |  | Finding Dory (2016) | £70,909 | £232,516 | £42,604,905 | -11% | 14 |
| 16 (new) | | Shivaay (2016) | £40,255 | £40,255 | £40,255 | new | 1 |
| 17 (new) |  | Train to Busan (2016) | £38,183 | £38,183 | £38,183 | new | 1 |
| 18 (new) | | Kodi (2016) | £34,216 | £34,216 | £34,216 | new | 1 |
| 19 (18) | | My Scientology Movie (2016) | £32,379 | £83,488 | £963,116 | -41% | 4 |
| 20 (17) |  | American Honey (2016) | £25,126 | £71,192 | £383,972 | -63% | 3 |
| 21 (new) | | After Love (2016) | £23,070 | £23,070 | £23,070 | new | 1 |
| 22 (new) | | Lo and Behold (2016) | £19,936 | £19,936 | £19,936 | new | 1 |
| 23 (new) |  | Ethel and Ernest (2016) | £19,202 | £19,202 | £19,202 | new | 1 |
| 24 (new) |  | Kaashmora (2016) | £19,190 | £19,190 | £19,190 | new | 1 |
| 25 (new) |  | Starfish (2016) | £10,692 | £10,692 | £10,692 | new | 1 |
| 26 (21) |  | The Beatles: Eight Days a Week - The Touring Years (2016) | £8,871 | £23,045 | £1,085,353 | -62% | 7 |
| 27 (re) |  | League of Legends World Championship Finals Viewing Party 2016 (2016) | £8,100 | £8,100 | £579 | re | 1 |
| 28 (new) | | Luck Key (2016) | £7,789 | £7,789 | £7,789 | new | 1 |
| 29 (new) | | Burn Burn Burn (2016) | £7,476 | £7,476 | £7,476 | new | 1 |
| 30 (24) |  | Supersonic (2016) | £7,334 | £17,465 | £730,404 | -54% | 4 |
| 31 (27) |  | The Infiltrator (2016) | £4,893 | £9,380 | £1,079,313 | -19% | 7 |
| 32 (40) |  | Miss Saigon 25th Anniversary Performance (2016) | £4,851 | £-17,376 | £2,021,112 | 70% | 3 |
| 33 (35) |  | The Girl With All the Gifts (2016) | £4,039 | £6,590 | £1,070,472 | 27% | 6 |
| 34 (30) |  | Anthropoid (2016) | £3,526 | £9,931 | £794,560 | -33% | 8 |
| 35 (new) | | Into the Inferno (2016) | £3,018 | £3,018 | £3,018 | new | 1 |
| 36 (31) |  | Brotherhood (2016) | £2,962 | £4,867 | £3,694,889 | -30% | 9 |
| 37 (28) |  | Jason Bourne (2016) | £2,899 | £6,455 | £23,131,853 | -49% | 14 |
| 38 (26) |  | Swallows and Amazons (2016) | £2,504 | £22,730 | £3,060,652 | -66% | 11 |
| 39 (41) | | King Lear: RSC Live 2016 (2016) | £1,765 | £3,601 | £415,148 | 19% | 3 |
| 40 (36) | | Under the Shadow (2016) | £986 | £4,322 | £69,193 | -64% | 5 |
| 41 (19) | | War On Everyone (2016) | £651 | £23,860 | £412,602 | -98% | 4 |
| 42 (23) | | Littlescreen (2016) | £596 | £2,005 | £19,580 | -97% | 2 |
| 43 (47) | | The Greasy Strangler (2016) | £586 | £1,558 | £17,036 | -26% | 4 |
| 44 (50) | | The Deep Blue Sea: NT Live 2016 (2016) | £510 | £510 | £718,607 | -11% | 8 |
| 45 (new) |  | The Comedians Guide to Survival (2016) | £78 | £78 | £78 | new | 1 |
| 46 (new) |  | Capture Kill Release (2016) | £59 | £59 | £59 | new | 1 |
| 47 (53) |  | Sour Grapes (2016) | £12 | £174 | £10,259 | -92% | 5 |