| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | André Rieu's 2022 Maastricht Concert: Happy Days Are Here Again (2022) | £798,706 | £798,706 | £798,706 | new | 1 |
| 2 (new) |  | Beast (2022) | £600,259 | £600,259 | £600,259 | new | 1 |
| 3 (3) |  | DC League of Super-Pets (2022) | £598,985 | £1,701,109 | £12,289,085 | -26% | 5 |
| 4 (2) |  | Bullet Train (2022) | £593,044 | £1,277,087 | £8,153,229 | -29% | 4 |
| 5 (1) |  | Nope (2022) | £576,643 | £1,429,937 | £5,999,801 | -50% | 3 |
| 6 (4) |  | Minions: The Rise of Gru (2022) | £573,512 | £1,652,272 | £42,385,150 | -24% | 9 |
| 7 (7) |  | Top Gun: Maverick (2022) | £549,490 | £1,028,779 | £80,595,677 | 6% | 14 |
| 8 (8) |  | Elvis (2022) | £381,965 | £884,366 | £25,843,357 | -23% | 10 |
| 9 (9) |  | Thor: Love and Thunder (2022) | £322,300 | £801,372 | £36,544,083 | -34% | 8 |
| 10 (6) |  | Fisherman's Friends: One and All (2022) | £316,523 | £1,133,593 | £1,789,886 | -52% | 2 |
| 11 (10) |  | Orphan: First Kill (2022) | £313,769 | £702,564 | £1,137,165 | -28% | 2 |
| 12 (new) |  | The Invitation (2022) | £261,791 | £261,791 | £261,791 | new | 1 |
| 13 (11) |  | Where the Crawdad's Sing (2022) | £167,427 | £483,783 | £7,378,729 | -39% | 6 |
| 14 (5) |  | Dragon Ball Super: Super Hero (2022) | £123,691 | £382,859 | £1,046,149 | -81% | 2 |
| 15 (new) |  | Liger (2022) | £102,178 | £102,178 | £102,178 | new | 1 |