| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Ice Age: The Meltdown (2006) | $68,033,544 | $68,033,544 | $68,033,544 | new | 1 |
| 2 (1) |  | Inside Man (2006) | $15,437,760 | $23,553,110 | $52,508,055 | -47% | 2 |
| 3 (new) |  | ATL (2006) | $11,554,404 | $11,554,404 | $11,554,404 | new | 1 |
| 4 (4) |  | Failure to Launch (2006) | $6,463,434 | $9,550,895 | $73,088,790 | -38% | 4 |
| 5 (2) |  | V For Vendetta (2006) | $6,295,358 | $10,453,490 | $56,659,439 | -49% | 3 |
| 6 (3) |  | Stay Alive (2006) | $4,506,719 | $6,554,208 | $17,280,614 | -58% | 2 |
| 7 (6) |  | She's the Man (2006) | $4,429,426 | $6,278,535 | $26,622,732 | -39% | 3 |
| 8 (new) |  | Slither (2006) | $3,880,270 | $3,880,270 | $3,880,270 | new | 1 |
| 9 (5) |  | The Shaggy Dog (2006) | $3,242,414 | $5,731,013 | $53,554,291 | -64% | 4 |
| 10 (new) |  | Basic Instinct 2 (2006) | $3,201,420 | $3,201,420 | $3,201,420 | new | 1 |
| 11 (7) | | Larry the Cable Guy: Health Inspector (2006) | $3,159,370 | $4,536,599 | $11,459,366 | -54% | 2 |
| 12 (8) |  | The Hills Have Eyes (2006) | $1,887,636 | $3,286,038 | $39,003,204 | -57% | 4 |
| 13 (15) |  | Thank You For Smoking (2006) | $1,606,328 | $1,967,374 | $3,349,398 | 38% | 3 |
| 14 (9) |  | Eight Below (2006) | $967,928 | $2,034,367 | $79,172,307 | -64% | 7 |
| 15 (10) |  | 16 Blocks (2006) | $707,401 | $1,522,439 | $35,526,665 | -67% | 5 |
| 16 (17) |  | Deep Sea 3D (2006) | $469,140 | $861,224 | $4,468,849 | -24% | 5 |
| 17 (12) |  | Madea's Family Reunion (2006) | $433,724 | $757,715 | $62,802,119 | -68% | 6 |
| 18 (11) |  | The Pink Panther (2006) | $418,425 | $936,131 | $81,688,700 | -71% | 8 |
| 19 (30) |  | Big Mommas House 2 (2006) | $382,560 | $459,633 | $69,226,041 | 43% | 10 |
| 20 (13) |  | Aquamarine (2006) | $380,030 | $661,184 | $18,007,080 | -64% | 5 |
| 21 (18) |  | The Chronicles of Narnia: The Lion the Witch and the Wardrobe (2005) | $350,327 | $560,063 | $291,171,963 | -30% | 17 |
| 22 (24) |  | Tsotsi (2006) | $295,376 | $389,397 | $1,639,397 | 4% | 6 |
| 23 (14) |  | Curious George (2006) | $282,495 | $652,715 | $57,542,530 | -72% | 8 |
| 24 (25) |  | The Worlds Fastest Indian (2005) | $204,665 | $333,373 | $4,123,562 | -26% | 9 |
| 25 (16) |  | Date Movie (2006) | $201,169 | $378,000 | $47,876,798 | -68% | 7 |
| 26 (27) |  | Mrs. Henderson Presents (2005) | $169,724 | $272,757 | $10,599,863 | -30% | 17 |
| 27 (20) |  | Final Destination 3 (2006) | $166,362 | $299,913 | $53,791,913 | -52% | 8 |
| 28 (26) |  | Nanny Mcphee (2005) | $153,520 | $261,860 | $46,487,425 | -44% | 10 |
| 29 (19) |  | Firewall (2006) | $134,842 | $286,277 | $48,061,767 | -70% | 8 |
| 30 (37) |  | Magnificent Desolation: Walking On the Moon (2005) | $133,793 | $317,290 | $9,626,353 | -11% | 27 |
| 31 (28) |  | The Three Burials of Melquiades Estrada (2006) | $132,024 | $225,935 | $4,575,126 | -41% | 8 |
| 32 (23) |  | Brokeback Mountain (2006) | $114,193 | $254,991 | $82,856,991 | -60% | 17 |
| 33 (32) |  | Syriana (2005) | $94,496 | $181,525 | $50,680,309 | -50% | 18 |
| 34 (33) |  | King Kong (2005) | $93,010 | $162,575 | $218,051,260 | -50% | 16 |
| 35 (new) |  | Marilyn Hotchkiss' Ballroom Dancing & Charm School (2005) | $92,668 | $92,668 | $92,668 | new | 1 |
| 36 (40) | | Neil Young Heart of Gold (2006) | $86,793 | $130,247 | $1,413,815 | -18% | 8 |
| 37 (39) |  | Harry Potter and the Goblet of Fire (2005) | $86,184 | $116,642 | $289,994,397 | -32% | 19 |
| 38 (new) |  | Brick (2006) | $83,574 | $83,574 | $83,574 | new | 1 |
| 39 (29) |  | Transamerica (2006) | $82,681 | $153,978 | $8,713,873 | -62% | 17 |
| 40 (42) |  | Joyeux Noel (2005) | $77,157 | $122,592 | $690,487 | -21% | 5 |
| 41 (re) | | Wild Safari a South African Adventure (2005) | $72,557 | $72,557 | $8,586,461 | re | 33 |
| 42 (45) | | Roving Mars () | $70,165 | $149,411 | $2,513,228 | -11% | 10 |
| 43 (22) |  | The Libertine (2005) | $68,875 | $202,507 | $4,756,532 | -78% | 5 |
| 44 (36) |  | Crash (2004) | $68,581 | $116,568 | $54,557,348 | -55% | 24 |
| 45 (new) |  | Adam and Steve (2005) | $66,429 | $66,429 | $66,429 | new | 1 |
| 46 (46) | | Cache () | $64,669 | $116,024 | $3,381,102 | -15% | 15 |
| 47 (38) |  | Ask the Dust (2006) | $61,403 | $120,203 | $630,802 | -55% | 4 |
| 48 (44) |  | Cheaper By the Dozen 2 (2005) | $59,254 | $97,952 | $82,407,457 | -33% | 15 |
| 49 (34) |  | Capote (2006) | $56,818 | $129,408 | $28,337,516 | -68% | 26 |
| 50 (31) | | Dave Chappelles Block Party () | $55,731 | $139,528 | $11,694,528 | -73% | 5 |
| 51 (35) | | Find Me Guilty (2006) | $54,132 | $129,249 | $1,127,362 | -65% | 3 |
| 52 (98) |  | Annapolis (2006) | $53,732 | $55,832 | $17,074,684 | 92% | 10 |
| 53 (41) |  | Walk the Line (2006) | $49,057 | $85,016 | $119,402,843 | -50% | 19 |
| 54 (51) | | Boynton Beach Club () | $43,294 | $76,188 | $242,623 | -25% | 3 |
| 55 (59) | | Sophie Scholl: The Final Days () | $41,408 | $58,234 | $327,381 | 18% | 7 |
| 56 (48) | | Why We Fight () | $39,138 | $76,087 | $1,222,928 | -39% | 11 |
| 57 (52) | | C.S.A.: The Confederate States of America () | $37,915 | $65,073 | $453,651 | -32% | 14 |
| 58 (47) | | Church Ball () | $36,555 | $69,760 | $337,606 | -49% | 3 |
| 59 (21) |  | Ultraviolet (2006) | $35,640 | $163,844 | $18,500,966 | -89% | 5 |
| 60 (43) |  | Chicken Little (2005) | $33,084 | $69,342 | $135,359,110 | -64% | 21 |
| 61 (49) | | A Cock and Bull Story (2006) | $30,889 | $54,022 | $1,164,177 | -51% | 10 |
| 62 (56) | | The Child () | $30,599 | $49,656 | $94,193 | -31% | 2 |
| 63 (57) | | Being Cyrus () | $30,000 | $39,522 | $80,266 | -26% | 2 |
| 64 (74) | | Lonesome Jim (2005) | $28,418 | $33,093 | $46,891 | 51% | 2 |
| 65 (54) |  | Hoodwinked (2006) | $28,060 | $50,221 | $51,028,777 | -40% | 12 |
| 66 (new) | | The Devil and Daniel Johnston () | $23,192 | $23,192 | $23,192 | new | 1 |
| 67 (61) | | Galapagos () | $21,942 | $44,929 | $16,078,840 | -34% | 190 |
| 68 (63) | | Don't Come Knocking (2005) | $20,604 | $35,629 | $110,272 | -33% | 3 |
| 69 (62) |  | The White Countess (2005) | $18,350 | $26,829 | $1,601,665 | -42% | 15 |
| 70 (re) | | Awesome I Fuckin Shot That () | $18,074 | $18,074 | $144,070 | re | 1 |
| 71 (re) | | Drawing Restraint 9 (2005) | $18,011 | $18,011 | $27,387 | re | 1 |
| 72 (50) | | Steve Harvey Don't Trip He Aint Through With Me Yet () | $16,379 | $33,046 | $299,565 | -73% | 3 |
| 73 (60) |  | Running Scared (2006) | $15,209 | $29,834 | $6,855,137 | -55% | 6 |
| 74 (65) |  | The New World (2005) | $14,280 | $31,230 | $12,712,093 | -44% | 13 |
| 75 (76) | | Ballets Russes () | $14,202 | $38,843 | $780,251 | 20% | 22 |
| 76 (81) | | Rape of the Soul () | $12,828 | $13,230 | $39,975 | 20% | 3 |
| 77 (67) | | Summer Storm () | $12,538 | $27,094 | $56,701 | -50% | 3 |
| 78 (83) | | The Beauty Academy of Kabul () | $12,238 | $16,492 | $30,981 | 21% | 5 |
| 79 (73) | | The Aryan Couple () | $10,556 | $17,728 | $290,211 | -31% | 7 |
| 80 (70) | | The Syrian Bride () | $10,494 | $14,943 | $240,596 | -36% | 18 |
| 81 (69) | | Taxi No 9 2 11 Nau Do Gyarah () | $10,034 | $14,319 | $291,048 | -46% | 6 |
| 82 (68) | | Game 6 (2005) | $9,868 | $33,260 | $85,196 | -50% | 4 |
| 83 (64) |  | Night Watch (2004) | $9,763 | $26,084 | $1,454,092 | -66% | 7 |
| 84 (66) | | Duck Season () | $8,209 | $19,103 | $113,318 | -68% | 4 |
| 85 (55) |  | The Magic Roundabout (2004) | $8,075 | $25,297 | $7,408,290 | -82% | 6 |
| 86 (71) |  | Glory Road () | $7,981 | $13,730 | $42,343,615 | -49% | 12 |
| 87 (78) | | The Boys of Baraka () | $7,627 | $14,083 | $295,941 | -30% | 15 |
| 88 (75) | | T Rex Back to the Cretaceous () | $7,053 | $10,414 | $52,588,186 | -43% | 272 |
| 89 (re) | | Darwins Nightmare () | $6,895 | $6,895 | $191,004 | re | 22 |
| 90 (88) | | Pulse a Stomp Odyssey () | $6,800 | $6,800 | $9,997,314 | -8% | 107 |
| 91 (new) | | Tibet a Buddhist Trilogy () | $6,596 | $6,596 | $6,596 | new | 1 |
| 92 (113) |  | Winter Passing (2005) | $6,278 | $6,570 | $94,670 | 87% | 7 |
| 93 (93) | | Fateless (2005) | $6,174 | $9,136 | $169,078 | 12% | 13 |
| 94 (90) |  | Aliens of the Deep (2005) | $5,744 | $10,103 | $7,758,129 | -10% | 61 |
| 95 (new) | | Swimmers (2005) | $5,644 | $5,644 | $5,644 | new | 1 |
| 96 (72) | | Stoned () | $5,506 | $13,338 | $28,747 | -64% | 2 |
| 97 (re) | | Brooklyn Lobster () | $4,856 | $4,856 | $137,121 | re | 15 |
| 98 (102) | | Our Brand Is Crisis () | $4,632 | $5,436 | $38,579 | 42% | 5 |
| 99 (re) | | Haunted Castle (2001) | $4,200 | $4,200 | $12,562,388 | re | 176 |
| 100 (re) | | The Intruder () | $3,774 | $3,774 | $36,553 | re | 9 |
| 101 (80) | | Unknown White Male () | $3,752 | $7,297 | $111,448 | -64% | 5 |
| 102 (105) |  | Evil (2003) | $3,689 | $4,482 | $10,301 | 51% | 3 |
| 103 (re) | | Beyond Honor () | $3,286 | $3,286 | $5,063 | re | 2 |
| 104 (new) | | Iron Island (2005) | $3,093 | $3,093 | $3,093 | new | 1 |
| 105 (re) | | Yang Ban Xi the 8 Modelworks () | $2,875 | $2,875 | $5,010 | re | 1 |
| 106 (91) | | Go For Zucker () | $2,825 | $6,210 | $69,434 | -54% | 14 |
| 107 (108) | | Before the Fall () | $2,814 | $3,378 | $124,550 | 45% | 21 |
| 108 (99) | | Nine Lives (2005) | $2,785 | $3,522 | $451,587 | -15% | 24 |
| 109 (re) | | Shakespeare Behind Bars () | $2,347 | $2,347 | $6,834 | re | 2 |
| 110 (92) |  | Space Station 3D (2002) | $2,279 | $6,627 | $64,738,299 | -60% | 196 |
| 111 (84) |  | American Gun (2005) | $2,261 | $4,839 | $15,238 | -76% | 2 |
| 112 (77) | | Rang De Basanti (2006) | $2,144 | $4,279 | $2,197,331 | -80% | 10 |
| 113 (106) | | Touch the Sound a Sound Journey With Evelyn Glennie () | $2,135 | $3,699 | $170,135 | 16% | 24 |
| 114 (112) | | Battle In Heaven () | $1,929 | $3,184 | $63,533 | 51% | 7 |
| 115 (87) | | 2005 Academy Award Nominated Short Films () | $1,733 | $4,904 | $131,849 | -77% | 6 |
| 116 (97) | | Trudell () | $1,597 | $3,801 | $25,645 | -62% | 8 |
| 117 (82) | | Tamara () | $1,574 | $1,965 | $180,591 | -84% | 9 |
| 118 (re) | | Gilles Wife () | $1,456 | $1,456 | $22,639 | re | 7 |
| 119 (re) | | New York Doll () | $1,359 | $1,359 | $219,461 | re | 17 |
| 120 (100) | | After Innocence () | $1,246 | $2,485 | $108,212 | -60% | 18 |
| 121 (re) | | Heading South (2006) | $1,145 | $1,145 | $4,117 | re | 4 |
| 122 (re) | | Take My Eyes () | $865 | $865 | $11,577 | re | 2 |
| 123 (re) | | Gay Sex In the 70s () | $774 | $774 | $240,385 | re | 15 |
| 124 (re) |  | Alien Adventure (1999) | $750 | $750 | $4,983,886 | re | 190 |
| 125 (re) | | Encounter In the Third Dimension () | $700 | $700 | $7,161,335 | re | 195 |
| 126 (85) | | The Zodiac () | $615 | $4,522 | $44,785 | -93% | 3 |
| 127 (re) | | When the Sea Rises () | $546 | $546 | $23,768 | re | 5 |
| 128 (re) |  | Loggerheads (2005) | $255 | $255 | $115,169 | re | 21 |
| 129 (109) | | Suits On the Loose () | $173 | $4,320 | $73,300 | -84% | 9 |
| 130 (104) | | Garcon Stupide () | $167 | $1,992 | $151,643 | -91% | 20 |