| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (1) |  | National Treasure: Book of Secrets (2008) | $20,062,684 | $46,795,384 | $170,870,795 | -44% | 3 |
| 2 (5) |  | Juno (2007) | $15,860,744 | $25,651,792 | $51,667,586 | 33% | 5 |
| 3 (3) |  | I Am Legend (2007) | $15,717,458 | $33,565,958 | $228,055,662 | -43% | 4 |
| 4 (2) |  | Alvin and the Chipmunks (2007) | $15,546,125 | $34,879,394 | $176,283,861 | -46% | 4 |
| 5 (new) |  | One Missed Call (2008) | $12,511,473 | $12,511,473 | $12,511,473 | new | 1 |
| 6 (4) |  | Charlie Wilsons War (2008) | $8,106,250 | $17,801,750 | $52,552,540 | -33% | 3 |
| 7 (7) |  | P.S. I Love You (2007) | $7,834,467 | $15,615,831 | $39,202,724 | -16% | 3 |
| 8 (8) |  | The Water Horse: Legend of the Deep (2008) | $6,230,489 | $14,026,205 | $30,823,470 | -32% | 2 |
| 9 (9) |  | Sweeney Todd: The Demon Barber of Fleet Street (2007) | $5,536,538 | $11,694,504 | $38,608,100 | -32% | 3 |
| 10 (14) |  | Atonement (2007) | $5,064,577 | $7,918,464 | $19,155,607 | 38% | 5 |
| 11 (6) |  | Aliens Vs. Predator: Requiem (2008) | $4,484,155 | $10,165,552 | $37,054,994 | -55% | 3 |
| 12 (11) |  | The Great Debaters (2007) | $4,250,948 | $8,757,577 | $22,013,765 | -29% | 3 |
| 13 (10) |  | Enchanted (2007) | $3,807,523 | $9,240,548 | $119,820,940 | -41% | 7 |
| 14 (12) |  | The Golden Compass (2007) | $2,730,000 | $6,652,000 | $65,521,000 | -37% | 5 |
| 15 (15) |  | No Country For Old Men (2008) | $1,843,000 | $3,720,000 | $44,785,000 | -17% | 9 |
| 16 (13) |  | Walk Hard the Dewey Cox Story (2008) | $1,800,986 | $4,861,119 | $17,284,363 | -53% | 3 |
| 17 (16) |  | The Kite Runner (2007) | $1,647,029 | $3,273,120 | $8,669,803 | -11% | 4 |
| 18 (22) |  | There Will Be Blood (2008) | $1,321,144 | $1,514,368 | $1,829,285 | 76% | 2 |
| 19 (28) |  | The Orphanage (2007) | $500,671 | $684,433 | $917,756 | 53% | 2 |
| 20 (18) | | The Savages (2008) | $457,343 | $854,755 | $2,545,266 | -13% | 6 |
| 21 (17) |  | Bee Movie (2007) | $443,220 | $981,704 | $125,196,072 | -31% | 10 |
| 22 (26) |  | The Diving Bell and the Butterfly (2008) | $345,685 | $576,217 | $1,458,913 | 21% | 6 |
| 23 (21) |  | The Bucket List (2008) | $326,786 | $677,265 | $1,308,990 | -3% | 2 |
| 24 (24) |  | American Gangster (2007) | $260,120 | $481,140 | $129,499,865 | -12% | 10 |
| 25 (25) |  | The Game Plan (2008) | $226,935 | $443,488 | $89,483,471 | -18% | 15 |
| 26 (23) |  | Beowulf (2007) | $206,417 | $432,538 | $81,512,692 | -32% | 8 |
| 27 (32) |  | Fred Claus (2007) | $200,384 | $350,202 | $71,651,318 | 1% | 9 |
| 28 (33) | | Sea Monsters a Prehistoric Adventure () | $190,866 | $566,032 | $6,258,285 | 27% | 13 |
| 29 (30) |  | Mr. Magoriums Wonder Emporium (2007) | $190,333 | $357,611 | $31,366,474 | -11% | 8 |
| 30 (27) |  | August Rush (2007) | $186,866 | $404,353 | $30,439,970 | -22% | 7 |
| 31 (45) |  | Dan In Real Life (2008) | $170,648 | $223,263 | $47,130,416 | 68% | 11 |
| 32 (36) | | Into the Wild (2007) | $147,185 | $260,714 | $17,252,013 | 14% | 16 |
| 33 (35) |  | Before the Devil Knows You're Dead (2007) | $135,188 | $228,760 | $6,652,931 | 1% | 11 |
| 34 (19) |  | This Christmas (2007) | $118,085 | $340,706 | $49,121,934 | -70% | 7 |
| 35 (20) | | The Perfect Holiday (2007) | $114,587 | $303,990 | $5,706,751 | -67% | 4 |
| 36 (re) | | Days of Darkness () | $108,809 | $108,809 | $1,205,437 | re | 3 |
| 37 (37) |  | I'm Not There (2007) | $108,525 | $204,860 | $3,292,335 | -7% | 7 |
| 38 (31) | | Like Stars On Earth () | $102,347 | $230,793 | $1,104,337 | -51% | 3 |
| 39 (38) |  | Hitman (2007) | $99,606 | $174,653 | $39,381,931 | -11% | 7 |
| 40 (39) |  | Persepolis (2008) | $76,867 | $150,268 | $313,640 | -13% | 3 |
| 41 (40) |  | Margot At the Wedding (2008) | $70,624 | $137,180 | $1,865,667 | -17% | 8 |
| 42 (44) |  | Michael Clayton (2007) | $69,830 | $122,031 | $39,254,140 | 15% | 14 |
| 43 (29) |  | The Polar Express (2004) | $68,956 | $164,751 | $2,432,361 | -68% | 48 |
| 44 (42) |  | Deep Sea 3D (2006) | $39,900 | $88,216 | $33,826,326 | -41% | 74 |
| 45 (43) |  | Awake (2007) | $38,916 | $83,599 | $14,139,086 | -41% | 6 |
| 46 (46) |  | Space Station 3D (2002) | $38,025 | $173,617 | $73,002,362 | -18% | 262 |
| 47 (51) | | Starting Out In the Evening () | $37,417 | $62,256 | $528,023 | 21% | 7 |
| 48 (52) |  | Blade Runner (1982) | $37,178 | $60,968 | $1,229,672 | 27% | 24 |
| 49 (47) | | Lars and the Real Girl (2007) | $36,886 | $73,406 | $5,760,558 | -15% | 13 |
| 50 (34) |  | Magnificent Desolation: Walking On the Moon (2005) | $36,264 | $332,404 | $22,378,846 | -74% | 98 |
| 51 (48) |  | The Darjeeling Limited (2007) | $31,512 | $58,289 | $11,743,402 | -16% | 15 |
| 52 (53) |  | The Mist (2007) | $24,776 | $38,982 | $25,335,717 | -2% | 7 |
| 53 (54) |  | Bella (2007) | $22,406 | $36,506 | $7,637,172 | -7% | 11 |
| 54 (55) | | Roving Mars () | $21,990 | $34,448 | $8,114,452 | -5% | 81 |
| 55 (57) |  | Lust, Caution (2008) | $19,873 | $40,039 | $4,563,185 | -4% | 15 |
| 56 (41) | | Santa Vs. the Snowman () | $17,893 | $56,383 | $766,198 | -77% | 61 |
| 57 (56) |  | Romance and Cigarettes (2005) | $16,961 | $30,081 | $513,680 | -21% | 14 |
| 58 (new) | | Undoing (2006) | $16,065 | $16,065 | $16,065 | new | 1 |
| 59 (50) | | Youth Without Youth (2007) | $10,817 | $37,623 | $166,602 | -64% | 4 |
| 60 (61) | | Honeydripper (2008) | $7,376 | $13,290 | $23,153 | -25% | 2 |
| 61 (63) |  | Control (2007) | $6,657 | $13,772 | $846,276 | 13% | 13 |
| 62 (58) | | Steep () | $5,785 | $23,107 | $78,878 | -64% | 3 |
| 63 (re) | | The Violin (2008) | $5,046 | $5,046 | $16,607 | re | 3 |
| 64 (82) |  | Sleuth (2007) | $4,341 | $5,295 | $338,264 | 83% | 12 |
| 65 (64) |  | The Assassination of Jesse James By the Coward Robert Ford (2007) | $3,653 | $7,653 | $3,884,370 | -14% | 16 |
| 66 (68) | | Diva () | $3,618 | $6,307 | $57,894 | 34% | 9 |
| 67 (re) | | The Killing of John Lennon () | $3,077 | $3,077 | $4,309 | re | 1 |
| 68 (67) |  | Lions For Lambs (2007) | $2,173 | $3,770 | $14,938,321 | -24% | 9 |
| 69 (59) | | Wild Safari a South African Adventure (2005) | $2,167 | $9,127 | $16,485,590 | -80% | 94 |
| 70 (re) | | Yiddish Theater a Love Story () | $2,033 | $2,033 | $18,908 | re | 5 |
| 71 (65) |  | Lagerfeld Confidential (2007) | $2,025 | $3,565 | $64,065 | -41% | 10 |
| 72 (re) | | How to Cook Your Life () | $2,018 | $2,018 | $64,650 | re | 9 |
| 73 (re) | | Outsourced (2006) | $2,017 | $2,017 | $160,987 | re | 11 |
| 74 (78) | | My Kid Could Paint That () | $1,918 | $3,343 | $216,484 | 46% | 14 |
| 75 (84) | | Kurt Cobain About a Son () | $1,784 | $2,054 | $76,777 | 65% | 14 |
| 76 (66) | | Joe Strummer the Future Is Unwritten () | $1,333 | $7,263 | $240,482 | -59% | 10 |
| 77 (re) | | Le Doulos () | $1,200 | $1,200 | $82,772 | re | 4 |
| 78 (69) |  | I Want Someone to Eat Cheese With (2006) | $947 | $2,467 | $194,568 | -57% | 17 |
| 79 (76) | | The Singing Revolution () | $914 | $1,486 | $18,787 | -26% | 5 |
| 80 (re) | | White Rainbow () | $862 | $862 | $9,988 | re | 2 |
| 81 (70) | | Arranged () | $845 | $3,668 | $20,174 | -61% | 3 |
| 82 (79) | | Shotgun Stories (2008) | $600 | $1,169 | $9,352 | -40% | 4 |
| 83 (re) | | El Inmigrante () | $483 | $483 | $10,347 | re | 3 |
| 84 (re) | | Ninas Heavenly Delights () | $396 | $396 | $8,256 | re | 5 |
| 85 (62) | | Haunted Castle (2001) | $365 | $5,605 | $13,511,936 | -95% | 217 |
| 86 (new) | | A Bloody Aria (2008) | $249 | $249 | $249 | new | 1 |
| 87 (72) | | Imaginary Witness Hollywood and the Holocaust () | $247 | $1,209 | $5,179 | -88% | 3 |
| 88 (91) |  | In the Valley of Elah (2007) | $158 | $158 | $6,765,181 | 37% | 17 |
| 89 (83) | | King Corn () | $75 | $612 | $97,062 | -89% | 13 |