| Title | Weekend | Week | Total | % Change | Total Weeks |
| 1 (new) |  | Sherlock Holmes: A Game of Shadows (2011) | $39,637,079 | $39,637,079 | $39,637,079 | new | 1 |
| 2 (new) |  | Alvin and the Chipmunks: Chip Wrecked (2011) | $23,244,744 | $23,244,744 | $23,244,744 | new | 1 |
| 3 (re) |  | Mission:Impossible - Ghost Protocol (2011) | $12,785,204 | $12,785,204 | $13,385,204 | re | 1 |
| 4 (1) |  | New Years Eve (2011) | $7,310,413 | $11,696,987 | $24,716,167 | -44% | 2 |
| 5 (2) |  | The Sitter (2012) | $4,608,681 | $8,078,552 | $17,929,987 | -53% | 2 |
| 6 (3) |  | The Twilight Saga: Breaking Dawn Part 1 (2011) | $4,197,893 | $6,925,305 | $266,327,974 | -46% | 5 |
| 7 (6) |  | Hugo (2011) | $3,707,848 | $5,740,990 | $39,155,709 | -39% | 4 |
| 8 (5) |  | Arthur Christmas (2011) | $3,554,286 | $5,101,033 | $38,501,631 | -45% | 4 |
| 9 (4) |  | The Muppets (2011) | $3,520,926 | $5,252,443 | $70,994,571 | -50% | 4 |
| 10 (18) |  | Young Adult (2011) | $3,403,159 | $3,532,820 | $3,843,083 | 91% | 2 |
| 11 (7) |  | The Descendants (2012) | $3,268,357 | $5,015,348 | $28,645,909 | -25% | 5 |
| 12 (9) |  | Jack and Jill (2012) | $1,228,843 | $1,979,244 | $70,506,629 | -60% | 6 |
| 13 (8) |  | Happy Feet Two (2011) | $1,077,329 | $2,119,468 | $58,909,873 | -71% | 5 |
| 14 (11) |  | Tower Heist (2011) | $901,025 | $1,666,555 | $75,788,740 | -62% | 7 |
| 15 (10) |  | Immortals (2011) | $851,371 | $2,020,644 | $81,889,376 | -65% | 6 |
| 16 (14) |  | My Week With Marilyn (2011) | $591,385 | $968,469 | $6,087,130 | -24% | 4 |
| 17 (12) |  | Puss In Boots (2011) | $465,209 | $901,928 | $142,775,402 | -71% | 8 |
| 18 (17) |  | Tinker, Tailor, Soldier, Spy (2011) | $456,777 | $568,986 | $879,548 | 32% | 2 |
| 19 (13) |  | J. Edgar (2012) | $386,494 | $957,786 | $35,718,897 | -67% | 6 |
| 20 (20) |  | Shame (2012) | $307,254 | $449,794 | $1,231,295 | 8% | 3 |
| 21 (19) |  | The Artist (2011) | $287,367 | $438,779 | $1,327,520 | -3% | 4 |
| 22 (21) |  | Dolphin Tale (2011) | $193,092 | $262,208 | $71,330,860 | -28% | 13 |
| 23 (15) |  | A Very Harold and Kumar Christmas (2011) | $175,064 | $426,871 | $34,413,079 | -63% | 7 |
| 24 (16) |  | In Time (2011) | $163,354 | $326,802 | $36,732,694 | -53% | 8 |
| 25 (38) |  | A Dangerous Method (2012) | $150,855 | $183,872 | $719,857 | 49% | 4 |
| 26 (22) |  | Melancholia (2011) | $133,914 | $271,763 | $2,243,206 | -42% | 6 |
| 27 (39) |  | Footloose (2011) | $123,746 | $150,322 | $51,292,776 | 43% | 10 |
| 28 (33) |  | The Polar Express (2004) | $108,303 | $162,891 | $460,048 | -6% | 73 |
| 29 (23) |  | Courageous (2011) | $102,879 | $181,039 | $33,514,678 | -47% | 12 |
| 30 (24) |  | Margin Call (2012) | $98,178 | $167,216 | $5,114,429 | -45% | 9 |
| 31 (27) |  | Paranormal Activity 3 (2011) | $91,616 | $154,474 | $103,783,478 | -36% | 9 |
| 32 (28) |  | Real Steel (2011) | $80,352 | $126,082 | $83,737,282 | -39% | 11 |
| 33 (new) |  | Carnage (2012) | $79,795 | $79,795 | $79,795 | new | 1 |
| 34 (29) |  | The Way (2010) | $79,295 | $145,731 | $3,988,533 | -39% | 11 |
| 35 (26) |  | Moneyball (2011) | $75,535 | $140,451 | $74,317,363 | -50% | 13 |
| 36 (35) |  | The Help (2011) | $72,053 | $121,080 | $169,345,705 | -32% | 19 |
| 37 (25) | | Like Crazy (2012) | $57,513 | $145,866 | $3,292,958 | -65% | 8 |
| 38 (42) |  | Born to Be Wild (2011) | $57,088 | $111,110 | $14,786,945 | -8% | 37 |
| 39 (32) |  | Midnight In Paris (2011) | $53,678 | $115,487 | $56,293,474 | -53% | 31 |
| 40 (34) | | The Skin I Live In (2011) | $51,798 | $60,144 | $2,942,230 | -53% | 10 |
| 41 (36) |  | The Three Musketeers (2011) | $50,210 | $87,807 | $20,315,324 | -42% | 9 |
| 42 (31) |  | The Ides of March (2011) | $45,589 | $99,943 | $40,567,824 | -62% | 11 |
| 43 (44) |  | Drive (2011) | $41,947 | $68,856 | $34,746,353 | -13% | 15 |
| 44 (30) | | The Greatest Miracle () | $37,652 | $87,291 | $492,945 | -69% | 10 |
| 45 (41) |  | 50/50 (2011) | $37,370 | $75,989 | $34,963,967 | -43% | 12 |
| 46 (50) |  | Hubble 3D (2010) | $36,447 | $71,628 | $29,762,240 | 7% | 86 |
| 47 (45) |  | Take Shelter (2011) | $27,608 | $54,255 | $1,627,470 | -42% | 12 |
| 48 (48) | | Le Havre (2012) | $24,257 | $41,068 | $358,706 | -37% | 8 |
| 49 (54) |  | The Lion King (1994) | $23,694 | $34,035 | $94,197,689 | -11% | 47 |
| 50 (43) | | Martha Marcy May Marlene (2011) | $21,602 | $49,193 | $2,870,277 | -58% | 9 |
| 51 (56) | | The Women On the 6th Floor (2012) | $18,684 | $31,061 | $428,097 | -20% | 11 |
| 52 (76) | | Being Elmo: A Puppeteers Journey (2012) | $13,903 | $15,861 | $208,276 | 77% | 9 |
| 53 (64) |  | Space Station 3D (2002) | $12,851 | $28,313 | $84,615,858 | 18% | 433 |
| 54 (53) |  | The Rum Diary (2011) | $12,429 | $29,580 | $13,100,042 | -58% | 8 |
| 55 (52) | | Pastorela () | $10,616 | $20,214 | $156,784 | -66% | 3 |
| 56 (63) |  | Tomboy (2011) | $9,881 | $16,873 | $89,753 | -14% | 5 |
| 57 (73) | | Sea Rex 3D Journey to a Prehistoric World () | $9,800 | $13,342 | $4,433,633 | 57% | 38 |
| 58 (57) | | Mozarts Sister (2012) | $9,421 | $22,813 | $669,081 | -44% | 18 |
| 59 (60) |  | Under the Sea 3D (2009) | $9,190 | $19,478 | $28,778,574 | -30% | 126 |
| 60 (new) | | Cook County () | $7,579 | $7,579 | $7,579 | new | 1 |
| 61 (61) | | Young Goethe In Love () | $7,298 | $11,811 | $93,211 | -42% | 7 |
| 62 (new) | | Cormans World Exploits of a Hollywood Rebel () | $7,000 | $7,000 | $7,000 | new | 1 |
| 63 (59) |  | Into the Abyss: A Tale of Death a Tale of Life (2012) | $6,389 | $16,497 | $216,262 | -60% | 6 |
| 64 (77) | | Crazy Wisdom the Life and Times of Chogyam Trungpa Rinpoche () | $6,381 | $10,096 | $43,106 | 51% | 4 |
| 65 (65) |  | The Guard (2011) | $6,341 | $11,763 | $5,325,090 | -38% | 21 |
| 66 (93) |  | The Interrupters (2011) | $6,282 | $6,964 | $267,763 | 79% | 16 |
| 67 (58) | | Eames the Architect and the Painter (2012) | $5,614 | $11,001 | $123,369 | -65% | 5 |
| 68 (75) | | Galapagos () | $5,486 | $9,117 | $18,046,670 | 29% | 319 |
| 69 (62) |  | Elite Squad 2: The Enemy Within (2011) | $5,014 | $11,771 | $80,487 | -56% | 6 |
| 70 (72) | | Blackthorn (2012) | $4,535 | $7,171 | $182,097 | 6% | 11 |
| 71 (68) |  | Sleeping Beauty (2011) | $4,529 | $7,967 | $29,004 | -24% | 3 |
| 72 (94) |  | Amigo (2010) | $3,489 | $3,920 | $178,285 | 66% | 14 |
| 73 (67) | | The Man Nobody Knew In Search of My Father Cia Spymaster William Colby () | $3,410 | $7,555 | $166,277 | -45% | 13 |
| 74 (89) | | My Reincarnation () | $3,121 | $4,520 | $38,011 | 41% | 7 |
| 75 (66) | | The Outrage (1964) | $3,082 | $7,905 | $26,159 | -62% | 3 |
| 76 (85) |  | House of Tolerance (2012) | $2,912 | $4,423 | $19,327 | 27% | 4 |
| 77 (96) | | London River (2010) | $2,600 | $2,786 | $4,100 | 60% | 2 |
| 78 (71) | | Happy Magic (2011) | $2,140 | $5,572 | $10,697 | -58% | 2 |
| 79 (70) | | Khodorkovsky (2012) | $1,759 | $5,378 | $25,480 | -70% | 3 |
| 80 (re) | | Rid of Me () | $1,660 | $1,660 | $5,382 | re | 3 |
| 81 (re) | | Addiction Incorporated () | $1,629 | $1,629 | $3,683 | re | 1 |
| 82 (104) |  | El Bulli Cooking In Progress (2012) | $1,628 | $3,083 | $193,613 | 58% | 20 |
| 83 (92) | | The Bride Wore Black (1968) | $1,412 | $1,670 | $17,661 | -2% | 4 |
| 84 (95) | | T Rex Back to the Cretaceous () | $1,298 | $1,593 | $53,236,489 | 12% | 347 |
| 85 (re) | | The Conquest () | $1,276 | $1,276 | $40,439 | re | 5 |
| 86 (88) | | The Mill and the Cross () | $1,045 | $2,717 | $263,508 | -46% | 14 |
| 87 (97) | | The Whale () | $1,028 | $1,764 | $57,986 | 3% | 14 |
| 88 (re) | | American Teacher () | $994 | $994 | $32,280 | re | 6 |
| 89 (re) | | Janes Journey () | $982 | $982 | $19,557 | re | 6 |
| 90 (103) | | Higher Ground () | $847 | $1,188 | $836,503 | 15% | 5 |
| 91 (84) | | Sholem Aleichem Laughing In the Darkness () | $789 | $1,439 | $838,235 | -65% | 24 |
| 92 (80) | | I Melt With You (2011) | $670 | $2,066 | $4,795 | -75% | 2 |
| 93 (99) | | The Look () | $645 | $991 | $12,664 | -32% | 4 |
| 94 (re) | | Littlerock () | $581 | $581 | $17,079 | re | 5 |
| 95 (90) | | Sigur Ros Inni () | $572 | $2,427 | $116,398 | -66% | 8 |
| 96 (re) | | King of Devil's Island (2012) | $554 | $554 | $2,345 | re | 2 |
| 97 (79) | | Revenge of the Electric Car (2012) | $470 | $1,171 | $150,307 | -83% | 9 |
| 98 (re) |  | American: The Bill Hicks Story (2010) | $432 | $432 | $91,306 | re | 11 |
| 99 (re) | | My Joy () | $352 | $352 | $5,457 | re | 3 |
| 100 (102) | | Summer () | $349 | $349 | $37,804 | -56% | 15 |
| 101 (110) | | Hell and Back Again (2011) | $346 | $345 | $34,637 | -14% | 10 |
| 102 (re) |  | 3 (2012) | $288 | $288 | $59,774 | re | 12 |
| 103 (101) |  | Answers to Nothing (2011) | $157 | $725 | $22,029 | -82% | 3 |
| 104 (105) | | Restless (2025) | $141 | $388 | $163,141 | -79% | 5 |
| 105 (108) | | Four Adventures of Reinette and Mirabelle () | $80 | $80 | $18,169 | -84% | 9 |
| 106 (106) | | Paul Goodman Changed My Life () | $17 | $67 | $24,333 | -97% | 7 |